HPE 800GB NVMe Gen4 Mixed Use SFF U.3 Multi-Vendor SSD

The HPE P64999-B21 is an 800GB NVMe Gen4 U.3 Small Form Factor solid state drive delivering mainstream mixed-use performance with Gen4 PCIe bandwidth, validated for HPE ProLiant and Synergy server platforms requiring high-throughput, low-latency storage in production environments.

Key Features

• 800GB capacity with PCIe Gen4 NVMe for next-generation storage performance
• U.3 interface supporting NVMe, SAS, and SATA tri-mode backplane compatibility
• Mixed-use endurance optimized for both read and write-intensive workloads
• HPE Basic Carrier (BC) included for direct bay installation in supported servers
• Multi-Vendor (MV) qualified — HPE-validated third-party NAND for cost efficiency

Product Specifications

• Part Number: P64999-B21
• Manufacturer: HPE
• Capacity: 800GB
• Interface: NVMe PCIe Gen4 x4 (U.3)
• Form Factor: SFF 2.5-inch with Basic Carrier
• Workload Type: Mixed Use
• NAND Type: Multi-Vendor (MV) TLC

Storage Specifications

• Sequential Read: Up to 6,800 MB/s
• Sequential Write: Up to 2,700 MB/s
• Random Read (4K): Up to 1,000,000 IOPS
• Random Write (4K): Up to 200,000 IOPS
• Endurance (DWPD): 3 DWPD (Drive Writes Per Day)
• Hot-Plug: Yes (U.3 backplane dependent)

Performance Specifications

• MTBF: 2,000,000 hours
• Power Loss Protection: Yes
• Operating Temperature: 0°C to 70°C
• Interface Compatibility: U.3 tri-mode (NVMe/SAS/SATA backplane)

Use Cases

• Mixed read/write workloads in HPE ProLiant Gen10/Gen10 Plus servers
• Virtualization host storage requiring Gen4 NVMe IOPS and bandwidth
• Database primary storage with high sustained write endurance (3 DWPD)
• AI/ML inference storage requiring low-latency NVMe access in HPE platforms

Compatibility

• Compatible with HPE ProLiant DL360/DL380/DL560 Gen10 Plus with U.3 backplane
• Supported by HPE Synergy 480/660 Gen10 Plus compute modules
• Requires HPE Smart Array or NVMe-capable storage controller
• Managed via HPE iLO and HPE SSA (Smart Storage Administrator)

Frequently Asked Questions

What does U.3 mean and why does it matter?

U.3 is a tri-mode interface standard that supports NVMe, SAS, and SATA protocols over the same physical connector. It allows backplane flexibility — the same bay can accommodate different drive types depending on the controller configuration.

What is the difference between P64999-B21 and standard HPE NVMe SSDs?

The P64999-B21 is a Multi-Vendor (MV) drive, meaning HPE validates third-party NAND manufacturers for this SKU, offering equivalent performance at a more competitive price point compared to single-vendor HPE-branded drives.

Does this drive include the Basic Carrier?

Yes — the BC designation in the part name indicates a Basic Carrier is included, enabling direct installation into compatible HPE SFF drive bays without a separate carrier purchase.

The HPE P64999-B21 delivers Gen4 NVMe speed and mixed-use endurance in the flexible U.3 form factor — giving HPE ProLiant and Synergy administrators a cost-effective path to next-generation storage performance without sacrificing HPE platform validation or reliability.