HPE 480GB NVMe PCIe 3.0 x4 Mainstream Read-Intensive M.2 22110 SSD — P24188-B21

The HPE P24188-B21 is a 480GB NVMe PCIe 3.0 x4 read-intensive SSD in M.2 22110 form factor and is the standard option kit for HPE ProLiant Gen10 Plus and Gen11 servers. The M.2 22110 interface enables direct attachment to M.2 slots on ProLiant system boards and NVMe M.2 carriers, delivering high-performance boot and caching storage without consuming SFF drive bays in storage-dense configurations.

Key Features

• 480GB NVMe PCIe 3.0 x4 read-intensive M.2 22110 option kit — OS boot and cache SSD for Gen10 Plus/Gen11
• M.2 22110 form factor for direct system board or carrier attachment without SFF bay consumption
• Mainstream Performance tier — balanced NVMe PCIe 3.0 price-to-performance for read workloads
• Read-intensive TLC NAND for OS boot, vSphere datastore, and read-dominant caching workloads

Product Specifications

• Part Number: P24188-B21
• Manufacturer: HPE
• Capacity: 480GB
• Interface: PCIe 3.0 x4 NVMe
• Form Factor: M.2 22110
• Performance Tier: Mainstream Performance
• Workload Type: Read Intensive
• Target Platform: HPE ProLiant Gen10 Plus, Gen11

Storage Specifications

• Drive Type: NVMe SSD (PCIe 3.0 x4)
• Form Factor: M.2 22110 (110mm length)
• Workload Class: Read Intensive (~1 DWPD)
• Interface: PCIe 3.0 x4 NVMe via M.2 connector

Performance Specifications

• Interface Bandwidth: PCIe 3.0 x4 — up to ~3.5 GB/s sequential read for read-dominant workloads
• Endurance: Read-intensive TLC — optimized for OS boot and read-heavy caching applications
• Latency: NVMe low-latency random read for fast OS boot and hypervisor storage

Use Cases

• HPE ProLiant Gen10 Plus/Gen11 OS boot drive in M.2 22110 slot
• VMware vSphere and Hyper-V hypervisor boot SSD without SFF bay consumption
• Read-intensive caching and logging SSD attached via M.2 carrier on Gen10 Plus/Gen11
• Embedded NVMe storage for management and OS partitions on compute-optimized servers

Compatibility

• HPE ProLiant DL380/DL360 Gen10 Plus / Gen11 with M.2 22110 NVMe slot or M.2 carrier
• HPE ProLiant ML350 Gen10 Plus / Gen11 supporting M.2 22110 NVMe
• Requires M.2 22110-compatible slot or HPE M.2 NVMe carrier — verify with HPE QuickSpecs

Frequently Asked Questions

What is M.2 22110 and how does it differ from M.2 2280?

M.2 22110 is 22mm wide and 110mm long — longer than the common M.2 2280 (80mm). Server-grade M.2 22110 drives are used in enterprise platforms for higher capacity and thermal headroom. Ensure your ProLiant server or M.2 carrier supports the 110mm length before installation.

Is P24188-B21 interchangeable with P24886-001?

Yes — P24188-B21 is the option kit and P24886-001 is the spare part. Both are HPE 480GB NVMe PCIe 3.0 x4 mainstream read-intensive M.2 22110 SSDs with identical specifications — fully interchangeable in supported Gen10 Plus and Gen11 M.2 configurations.

Can P24188-B21 be used as a primary data drive or only for OS boot?

P24188-B21 can be used for OS boot, hypervisor installation, caching, or small-capacity NVMe data storage. At 480GB read-intensive capacity, it is best suited for OS, hypervisor, and read-dominant caching roles. For primary data workloads requiring higher endurance, a mixed-use M.2 NVMe SSD is recommended.

The HPE P24188-B21 480GB NVMe PCIe 3.0 x4 M.2 22110 read-intensive SSD option kit delivers efficient OS boot and caching storage for HPE ProLiant Gen10 Plus and Gen11. Order today — in stock at the lowest price.