HPE 10TB SATA 6Gb/s Business Critical 7200RPM 512e/ISE HDD with Low Profile Carrier — P53557-B21

The HPE P53557-B21 is a 10TB SATA 6Gb/s Business Critical 7200RPM hard drive with 512e and ISE (Instant Secure Erase) in 3.5-inch LFF form factor with Low Profile Carrier for HPE ProLiant Gen10 Plus and Gen11 servers. ISE enables rapid cryptographic drive erasure for secure decommissioning and redeployment, while Business Critical reliability ratings and 7200RPM spindle speed deliver sustained SATA HDD throughput for high-capacity nearline storage workloads.

Key Features

• 10TB SATA 6Gb/s Business Critical 7200RPM HDD with ISE — high-capacity secure-erase nearline storage
• ISE (Instant Secure Erase) for rapid cryptographic erasure during drive decommissioning or redeployment
• 512e Advanced Format for compatibility with modern OS and storage controller sector sizes
• Low Profile Carrier for 3.5-inch LFF hot-swap installation in HPE ProLiant LFF bays

Product Specifications

• Part Number: P53557-B21
• Manufacturer: HPE
• Capacity: 10TB
• Interface: SATA 6Gb/s
• Form Factor: 3.5-inch LFF with Low Profile Carrier
• RPM: 7200RPM
• Sector Size: 512e (Advanced Format)
• Security: ISE (Instant Secure Erase)
• Target Platform: HPE ProLiant Gen10 Plus, Gen11

Storage Specifications

• Drive Type: Nearline 7200RPM HDD (SATA 6Gb/s)
• Form Factor: 3.5-inch LFF Hot-Swap with Low Profile Carrier
• Sector Size: 512e (512-byte emulation with 4K physical sectors)
• Security: ISE — instant cryptographic erasure for secure decommissioning
• Workload Class: Business Critical nearline — high-capacity sustained throughput

Performance Specifications

• Interface Bandwidth: SATA 6Gb/s for nearline HDD workloads
• Spindle Speed: 7200RPM for sustained sequential throughput in nearline applications
• Cache: High-capacity buffer for sequential read/write performance optimization

Use Cases

• HPE ProLiant Gen10 Plus/Gen11 high-capacity 10TB SATA nearline storage with ISE capability
• Backup-to-disk, archive, and content repository requiring 10TB SATA HDD density
• Regulated and compliance environments requiring ISE for drive decommissioning and redeployment
• High-capacity SATA nearline storage with Business Critical reliability for ProLiant Gen10 Plus/Gen11

Compatibility

• HPE ProLiant DL380/DL360 Gen10 Plus / Gen11 with 3.5-inch LFF SATA bays
• HPE ProLiant ML350 Gen10 Plus / Gen11 with 3.5-inch SATA LFF drive bays
• Interchangeable with P54673-001 (512e without ISE) — verify ISE requirement before selecting variant

Frequently Asked Questions

What is ISE (Instant Secure Erase) and when is it required?

ISE uses hardware encryption to generate and discard an internal encryption key, rendering all drive data cryptographically inaccessible in seconds — far faster than overwrite-based erasure. ISE is required or recommended for regulated environments (HIPAA, PCI-DSS, government) where drives must be securely erased before decommissioning, redeployment, or return under warranty.

What is the difference between P53557-B21 (512e/ISE) and P54673-001 (512e)?

P53557-B21 includes ISE (Instant Secure Erase) for cryptographic drive erasure. P54673-001 is the standard 512e variant without ISE. Both are HPE 10TB SATA 6Gb/s Business Critical 7200RPM 3.5-inch LFF HDDs. Choose P53557-B21 when ISE is required for compliance; P54673-001 for standard deployments where ISE is not needed.

What is 512e and does it affect compatibility with older SATA controllers?

512e (512-byte emulation) uses 4K physical sectors but emulates 512-byte logical sectors for OS and controller compatibility. Most modern SATA controllers and operating systems support 512e without issues. For older controllers that only support native 512-byte physical sectors, verify compatibility before deploying 512e Advanced Format drives.

The HPE P53557-B21 10TB SATA 6Gb/s Business Critical 7200RPM 512e/ISE HDD with Low Profile Carrier delivers high-capacity secure nearline storage for HPE ProLiant Gen10 Plus and Gen11. Order today — in stock at the lowest price.